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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a343a17c2f2135b33b5b58eea7c2cbf5d6951da361cc7cc8274c8f234c62fa01' 
  AND token = '4oQTKgzwmE86oLHTeG2OS8zrUXzr7GWzK7mVsM0gMcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}