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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53668d9519a4c13b3c2b570f8f76a3f521b47af9188787022951e7baa982bd49' 
  AND token = 'bxNotSoNzTafy+pMoptM124H7NcEJL75jy41DgBz2qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}