SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c6915dbebd290b14f05d6e8587085de6afa508a631c7b8f8251960a0f15ce45' 
  AND token = 'uXK0QFub9eyEgxEry4GxtkfKtR1bPJxhx9LqTetPGB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}