SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c133bd76905f74002ae2a386f09da29bfa907d941eb36454f59dbdc1e4cc546b' 
  AND token = 'PB/9qMFeikrH6OpueoURqBKl9rRG/xTTwo3IiQVBnkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}