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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79a8c3b75e2a2301652468ede240173d9e56f350d2ad1761d78d71a0197ec254' 
  AND token = 'KVeEpnV2RMkmaFe2g1pEhVPmV3vk1EU4yxXObpwxrQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}