SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6004c7127e39eed5dc16b65cec6b60795519a03525d50b527e4be50cc64668b' 
  AND token = 'DPd+/GSMJlCgjsGkgYXXUR7VjJ2yK0pr2YE7QGP4GXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}