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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d55926e79b7466e1d15f6e93ab407399094d836edd3f1900a79f3968b49064' 
  AND token = '5+DH0iF0oVLyxZSLJVNI81MoJrPXb1o7QhICQflUKSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}