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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9e35643b4f04829fafece4e10ea71527b8241e199db0dd1373251cc1222420c' 
  AND token = '/6XL/bsZqLijjOiArT6+xfxEVN4GjzoeslA4NzW5Mzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}