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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c20a14a47146eac28e16c2b3016d755e72e3b3b4b567a4d4a7d178036663913' 
  AND token = '21Rfcp0Hd0UyBL5bRPW/neHCOb63xxowiOnSSlk/jWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}