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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0780871a2effadce908192a1dfe2cc6c0d594e75e16261551c92fa4ac7f4076' 
  AND token = 'EuVZwlrY4wWCMocQncOZSMm4uGVcdnrTrredqGq1oF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}