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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10c4e07c02a69e65e6d3686b9deeed46a90470ec6ea6db461c55ac0936892b0a' 
  AND token = '6C1F4y2NTF1mljQQfaNEGOYwbttgBMlNTUfY58B8qmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}