SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c59d1d04c8877f17ce18b6f1ad324c2ecdf2cad97a46118c2a4122b0887ab604' 
  AND token = 'js5bIHz1Vt4Lu9bVVqy3cPn8UOnTbbx5S/XFwOMiTNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}