SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943a779778d497fd21b093ee2e3fffa431ad62f3b452ac05561b022b9b6a18e1' 
  AND token = 'IBB1rf8UUjIxiRhMcRDl2mDDrBKYM6YrmRO0AjKn5Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}