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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3a4fb9dfede085778b3be36619cb59f8c45bd782bedecc9d29e7105dbc6e6e' 
  AND token = 'R2dWAqwBTRWrOUGRHcgl0sBiaONzrlK7rPN/fExILKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}