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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89b435efdf543aa4071a6c1aa456e92772ee9935b60133429c5944da3e5af3b4' 
  AND token = 'cVCYscPRwswfNB5dAdk6il9cMRy9rKa9gqDyCzHd+cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}