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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ecb46720f29e444927b58e22f024301c6da84ae3da43f45112d5df3dc774d47' 
  AND token = 'uPcRBTpIDcd2V25SAcQBuPDRksyNE0Zl1F6/H11AQR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}