SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1720d7acc550ad5d242536617232951b9a0b555e3aa7eb25d279f94cbf24d417' 
  AND token = 'gyZ7QSAS9f9YpVP0beVmUc4X6sUUYbju7F6V3ORtnmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}