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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd6523f8f01d09357b311552d35536d32ca840118f9db90a92c6c14f99bdd265' 
  AND token = '9IqTbnCbvpd7OGUNzErG3+fofjMolfzee3v358FCmvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}