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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa28393ff899a96d32e884af2f9afb0840d511eac2fce4145c1701d1bcfbca0' 
  AND token = '77bNQYtVhCMcwYtSoawcO8a+0aYJCrnk+gBoww4i3Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}