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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59be0ff183fdb3813ccf3a8867acdfe47eb3303a7edecc897d418d5ad53d8d77' 
  AND token = 'O681550WogrFNU1Tup1UDD3KNmElgq94qFU4spLkDmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}