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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a27f3e1ddac9dcd8db6a2416f6aed61102018d73f6fd7a5d24805ce9cb216451' 
  AND token = 'OcG42mefsqx1/bZSm1EQtiHfnhADXUX+tl2nPy408/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}