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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2ae1b11572f5bd52aa5fa3ae8ae3d297b3a651c9d5ae57a4b27139d2bc3f6ab' 
  AND token = 'N2I8S1hKvfKBUMNDTO19fd5q+NDcHUkb8iO8dUCa4nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}