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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8351c9779398bc233ed9efbb897e29c6288dcdf8ae3d2dd184335a1849bc622' 
  AND token = 'WteOj70pXyENNE6m3SjNxOGpltJeaEHWVZnrAgtUK2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}