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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5a58fd914f6c6ba97d9ba43569fcb02f67b39e38d133d7a1408c1c190a2897f' 
  AND token = 'CIX8YvR7701uz0+wB13CFWNA9aZ7L9QnlBhMES6CzB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}