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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd48a99040d62c797cd14d5301aab5739b960eeb5241854dfbe97e3e9f5e107e8' 
  AND token = 'VIkqZbFmyZdX/ZCTWg1xVJmpb8C9fdENpQK3vIefiOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}