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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '193135830a91047d0d6fd736b6dfc6b44a2090f8ec5206b3c1df1e9fd20cf457' 
  AND token = 'tydM1lTlUHymg2bq3QReg1H1NJil4xUEZXi0dtgWt2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}