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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6ac6d555003623466a9b2b50fbba197ff763e336d4a12bc33a8a7d009857d5' 
  AND token = 'EEKSDGDxGAYjDgQMaZXrhOewJ/4ziw8NncAM1Um704M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}