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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1314001745e4915bdeb1298d21635a60c2a7f1af02923be5b5141a6a52d9a394' 
  AND token = 'Up9DL6f/oUZdmGJUxvPeYPGZnW04zhDIWlp5Qx3J5wA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}