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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08ed3885d3a7e3bfed31ea36f34eeb46ec107427b9fcfcbbfe46df0e00633712' 
  AND token = '03Hlx27yQ4Bc5wBHEliJJPMcqHCNKiUOZsfRkFVx0wA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}