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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae0a81a33294b72dfd299e5c77de01c623d18b6a4234ac4afe69470475867f43' 
  AND token = 'OKt5SuMO6qn8pDG+rADcpo27F7IP35n+GzKDzWqyif0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}