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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '811b21842a8003e971a130cb95140152c04b158c395daec2f8996ac057d62c8c' 
  AND token = 's0ODy5STOxL6uuyQegVxxaUWY7j42ynxly2RVyHUrPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}