SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ce828c2d6e1eadbd1ec9010cea7e5fc0e88bdcb295bce0998b1e5d90571214c' 
  AND token = 'nut5weFdHCN+1gv/yBHW/VJw/5/clV7CteAHDYHt4wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}