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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6791ec4b4e0da1081e00a94a2b9351c712535ce9c212dd2cd837ef532cc669c' 
  AND token = 'pxbMryLNoErA+Ymj0K4auGRXsPFD7Ny69ADKklLe/mE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}