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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '818995c9c5c5bf1dd8fb085c552410db54aa05d660b8c7f7fc08ff8f19f20e49' 
  AND token = '368bLAWFHPAp0hInFFsTPrlxbPB9nSj7fsRiJ3OT31g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}