SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b96148a49d6cda610e566d8b46c221166e18101272b10d11b0a32aa6a833a54' 
  AND token = 'OjHQkZUdzd1kINmI29EKv5qGm7MBE/7Ye1K3ElS1LWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}