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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85a779bff27feb2e3cbaef1dcea4d0d642f9cb7b7040ef0ec8e9a1faef402176' 
  AND token = 'gtZZTtjvjd5u7b1Xp73XgKmGz+ki93el7CkAGyG/yKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}