SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50bf22c188258998559bffbf4163b477fa897c421cc3442858d923a8a14017e' 
  AND token = 'YVZEywSgqWfGR+coe8WWJhELAcOFWnu6oOADW/Z/Y2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}