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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a53bac6214f1c74ad12453ed2ec0ade9182f5de02ddb044f89910d3fd747d639' 
  AND token = '/lfGbkTu+wPoYQnfc7W/E7NgW7/dfoF3Z4bRUKLAwuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}