SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4287f1084a5504bae26831edcab169f8913b9e37c1400011421740f45ae917e' 
  AND token = 'sw50IUQj+PGj+chq7f3RX39YJnzgUf7HIpGUrJoLmsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}