SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '013301246c88fe85da45bfffdb372e2e738d9bacb974a4434a93a00ddde43edc' 
  AND token = 'dzxaZPVOPzbOGgPoosW/g097UaH26WTRqOfN9LjaWhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}