SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65367f8be53e08de1e20235fe931a01ac6077ab6a96929e7b3f8150504ec8d24' 
  AND token = 'iyvyeR2hpvUCNNukzFRGIW7+Lt7tuvdzHSl+s6WOZT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}