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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8190b56dbbcba8b3caa5559c8c6a210208167cb0ee6486f24ed0fd47e9d5999c' 
  AND token = '5oX2d4Tj0G1dKbJMzjp2S4fvtC1FvjxRQWv7wmpy5Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}