SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dea16bb2b9c8a15d456388149d68f5e1c525d16b563187569f04a7c05811bc3' 
  AND token = 'kqGe5xIuGAqx+43g/xI+czoSP4xG8KsWlFpc4s0v4A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}