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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c6e2dc36aa70248940b38a4a13bc38157ed4ce580416121c8063dd99d70cc3a' 
  AND token = 'h18S8HDF6EctbfhUwjYXGt0q+MN7S8v6qgdUp9Im+yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}