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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c678ff43c5c8d3d0c98b89ee0572fb039a24463b258722f01b4e0aae5853dd85' 
  AND token = '6JQHVBjjIxMa/du+cN1SWiGgVW1ntJkUx2PI7XdNA7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}