SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '680a1d2fa9addf3545e1fd09ea851d7f17939657954948a4014c244ff4a898ba' 
  AND token = 'h2LVTknTEiP+tAe91n4KgzvcfS01rrHPHOQQP5pfRM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}