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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '466c59a21fc121628d2587f1a7feca5bccc569fedffee975e6879c3d83e9bff8' 
  AND token = 'Qs6dMQU/M5e3HaCpGk54QwjXHDMCtMKzV1RgNvvpiW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}