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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51f624454af4229f6dca3a50c34bfb2c3d50a8d1161c07b981432c186c8fa0b7' 
  AND token = 'ZOjLeb4tHyo1sZc/ydNNICvEkSPno1G30sYO5hT9oAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}