SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fb4512f2e4161267cfae59cea1eee5d41c4e22b942329c639aa21b42ff0628e' 
  AND token = 'jsTXBBwIYugCpg6gnS93xleUjjb6nVX93A0tbkVsrkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}