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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c38e98fc340bb06678ec04cd626c6954ddfbe96b3157070e2bde2e74fdfb450' 
  AND token = 'UvR9Q99cSbZxO5OztM6DUu/NOtxO8a00c6FF8MCa1rU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}